In particle physics there are two types of substances one which is made up of particles known as matter and the other made up of anti-particles known as anti-matter.
Anti-particles are those which have same mass as that of the particles of the matter but different particle properties such as charge, etc... Electrons and Positrons, Neutrinos and anti-neutrinos are some examples.
Collision between particle and anti-particle lead to annihilation and release enormous amount of energy and particle and anti-particle again such as high energy photons, neutrinos, lower mass particle and anti-particle pairs.
The end result of annihilation is the release of energy equivalent to the total matter and anti-matter mass which is in accordance with the Einstein's famous Mass-Energy Equivalence relation, E=MC^2.
Like matter anti-particle combine to form anti-matter. For example, a positron (the anti-particle of the electron) and an anti-proton can form an anti-hydrogen atom. Physical principles indicate that complex anti-matter atomic nuclei are possible, as well as anti-atoms corresponding to the known chemical elements.
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